HTR7 polyclonal antibody
产品名称： HTR7 polyclonal antibody
英文名称： HTR7 polyclonal antibody
产品编号： PAB17022
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of HTR7.
- Immunogen:
- A synthetic peptide corresponding to human HTR7.
- Sequence:
- QNADYCRKKGHDS
- Host:
- Goat
- Theoretical MW (kDa):
- 49.5, 48, 53.6
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a) receptors in HeLa cells.
Sjogren B, Svenningsson P.Acta Physiol (Oxf). 2007 May;190(1):47-53.
- Entrez GeneID:
- 3363
- Protein Accession#:
- NP_000863.1
- Gene Name:
- HTR7
- Gene Alias:
- 5-HT7
- Gene Description:
- 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
- Omim ID:
- 182137
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq
- Other Designations:
- 5-hydroxytryptamine receptor 7,OTTHUMP00000020077,OTTHUMP00000020078,OTTHUMP00000020079,serotonin 5-HT-7 receptor
- Related Disease
- Acute Disease
- Alcoholism
- Alzheimer Disease
- Anorexia Nervosa
- Autistic Disorder
- Bulimia
- Cognition
- Cognition Disorders
- Fatigue
- Fatigue Syndrome, Chronic
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Mental Disorders
- Migraine Disorders
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenia
- Schizophrenic Psychology
- Weight Gain