分子量：Calculated MW: 67kDa/68kDa/71kDa
Observed MW: 45KDa

细胞定位：Cell membrane, GPI-anchor, Golgi apparatus, Lipid-anchor, Secreted

稀释方法：WB 1:500 - 1:2000
IF 1:10 - 1:100

总结：This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.