CBR3 monoclonal antibody, clone AT3C5
产品名称： CBR3 monoclonal antibody, clone AT3C5
英文名称： CBR3 monoclonal antibody, clone AT3C5
产品编号： MAB7557
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant CBR3.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-277 of human CBR3.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody reacts with human CBR3.
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3).
Lakhman SS, Ghosh D, Blanco JG.Drug Metab Dispos. 2005 Feb;33(2):254-7. Epub 2004 Nov 10.
- 2.
- Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2.
Watanabe K, Sugawara C, Ono A, Fukuzumi Y, Itakura S, Yamazaki M, Tashiro H, Osoegawa K, Soeda E, Nomura T.Genomics. 1998 Aug 15;52(1):95-100.
- Applications
- Western Blot (Cell lysate)
- Cell lysates of HepG2 (20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with CBR3 monoclonal antibody, clone AT3C5 (Cat # MAB7557) (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 874
- Protein Accession#:
- NP_001227
- Gene Name:
- CBR3
- Gene Alias:
- SDR21C2,hCBR3
- Gene Description:
- carbonyl reductase 3
- Omim ID:
- 603608
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq
- Other Designations:
- NADPH-dependent carbonyl reductase 3,carbonyl reductase (NADPH) 3,short chain dehydrogenase/reductase family 21C, member 2
- Gene Pathway
- Related Disease
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Genetic Predisposition to Disease
- Lung Neoplasms
- Neoplasms
- Obesity
- Ovarian Failure, Premature
- Polycystic Ovary Syndrome
- Puberty, Delayed
- Puberty, Precocious
- Pulmonary Disease, Chronic Obstructive
- Thrombophilia
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
- Werner syndrome