磷酸化毛细血管扩张性共济失调症突变蛋白抗体
产品名称: 磷酸化毛细血管扩张性共济失调症突变蛋白抗体
英文名称: phospho-ATM (Tyr170)
产品编号: bs-11707R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-01-23T14:13:33
使用范围: ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,
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ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).