分子量：Calculated MW: 24kDa/57kDa
Observed MW: 48kDa

细胞定位：Membrane, Peripheral membrane protein

稀释方法：WB 1:1000 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

总结：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.