MAPK8 monoclonal antibody (M01), clone 3H2
产品名称: MAPK8 monoclonal antibody (M01), clone 3H2
英文名称: MAPK8 monoclonal antibody (M01), clone 3H2
产品编号: H00005599-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse monoclonal antibody raised against a partial recombinant MAPK8.
 
- Immunogen:
 - MAPK8 (NP_620637, 318 a.a. ~ 428 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
 
- Sequence:
 - HPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEAAAGPLGCCR*
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Isotype:
 - IgG2a Kappa
 
- Storage Buffer:
 - In 1x PBS, pH 7.2
 
- Storage Instruction:
 - Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - Antibody Reactive Against Recombinant Protein.

Western Blot detection against Immunogen (38.21 KDa) . 
- MSDS:
 
Download
- Applications
 
- Western Blot (Transfected lysate)
 
- Western Blot analysis of MAPK8 expression in transfected 293T cell line by MAPK8 monoclonal antibody (M01), clone 3H2.
Lane 1: MAPK8 transfected lysate(48.3 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
 
- Western Blot (Recombinant protein)
 - Protocol Download
 
- Immunoprecipitation
 
- Immunoprecipitation of MAPK8 transfected lysate using anti-MAPK8 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with MAPK8 MaxPab rabbit polyclonal antibody.
 - Protocol Download
 
- Entrez GeneID:
 - 5599
 
- GeneBank Accession#:
 - NM_139049
 
- Protein Accession#:
 - NP_620637
 
- Gene Name:
 - MAPK8
 
- Gene Alias:
 - JNK,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1
 
- Gene Description:
 - mitogen-activated protein kinase 8
 
- Omim ID:
 - 601158
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
 
- Other Designations:
 - JNK1 alpha protein kinase,JNK1 beta protein kinase,JUN N-terminal kinase,OTTHUMP00000019552,OTTHUMP00000019555,OTTHUMP00000019556,OTTHUMP00000019558,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein
 
- Interactome
 
- Gene Pathway
 
- Adipocytokine signaling pathway
 - Colorectal cancer
 - Epithelial cell signaling in Helicobacter pylori infection
 - ErbB signaling pathway
 - Fc epsilon RI signaling pathway
 - Focal adhesion
 - GnRH signaling pathway
 - Insulin signaling pathway
 - MAPK signaling pathway
 - Neurotrophin signaling pathway
 - Pancreatic cancer
 - Pathways in cancer
 - Toll-like receptor signaling pathway
 - Type II diabetes mellitus
 - Wnt signaling pathway
 

