c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit
产品名称： c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit
英文名称： c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit
产品编号： KA0058
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit is a single-site, non-quantitative immunoassay for kinase activity of recombinant catalytic domain of c-Src. Plates are pre-coated with a newly designed "Tyrosine kinase-binding module-1", which can easily bind recombinant catalytic domain of c-Src, subsequently activate c-Src kinase activity on a microtiter plate. The detector antibody is PY-39, an antibody that specifically detects the phosphotyrosine residue on recombinant catalytic domain of c-Src itself, which means that this kit measures the intensity of autophosphorylation of c-Src catalytic domain.
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Dose dependent curve
Dose dependent curve of recombinant c-Src catalytic domain enzyme reaction.
- Protocol:
Protocol Download
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Entrez GeneID:
- 6714
- Gene Name:
- SRC
- Gene Alias:
- ASV,SRC1,c-SRC,p60-Src
- Gene Description:
- v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
- Omim ID:
- 190090
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000174476,OTTHUMP00000174477,proto-oncogene tyrosine-protein kinase SRC,protooncogene SRC, Rous sarcoma,tyrosine kinase pp60c-src,tyrosine-protein kinase SRC-1
- Related Disease